The Effect of the Rising Abdominal Perfusion Pressure on Kidney Function Assessed by the RIFLE Criteria in Critically Ill Patients with Multiorgan Dysfunction
American Journal of Life Sciences
Volume 2, Issue 6, December 2014, Pages: 333-337
Received: Oct. 21, 2014;
Accepted: Nov. 4, 2014;
Published: Nov. 17, 2014
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Hatem H. Elatroush, Critical Care Department Cairo University, Cairo, Egypt
Nashwa Abed, Critical Care Department Cairo University, Cairo, Egypt
Amna A. Metwaly, Critical Care Department Theodor Bilhars research institute, Giza, Egypt
Mohamed I. Afify, Critical Care Department Cairo University, Cairo, Egypt
Mayada M. Hussien, Critical Care Department Theodor Bilhars research institute, Giza, Egypt
Abdominal perfusion pressure (APP) is a novel, clinically measurable parameter to explain the circulatory compromise in the abdominal cavity, defined as the difference between the mean arterial pressure (MAP) and the intrabdominal pressure (IAP). Kidneys are especially vulnerable intrabdominal organ to the circulatory compromise and the third spacing in multiorgan dysfunction syndrome (MODS) patients. And this study was to evaluate the relationship of the APP to AKI assessed by RIFLE Patients and methods: 106 MODS patients were included in the study, routine laboratory investigations and vital signs were recorded and APP and RIFLE score were assessed daily for the first three days. Results: AKI patients had lower APP (86.3 ± 9.0 vs 78.4 ± 18.5 P 0.009). Patients with APP < 60mmHg showed worse RIFLE scores (0=0/18, R=1/6, I=2/27, F=13/39 p=0.03). APP was significantly correlated with urine output (r=0.239 P 0.013). Conclusion Low APP causes deterioration of kidney function and oliguria is the first and sensitive predictor.
Hatem H. Elatroush,
Amna A. Metwaly,
Mohamed I. Afify,
Mayada M. Hussien,
The Effect of the Rising Abdominal Perfusion Pressure on Kidney Function Assessed by the RIFLE Criteria in Critically Ill Patients with Multiorgan Dysfunction, American Journal of Life Sciences.
Vol. 2, No. 6,
2014, pp. 333-337.
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