Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata
American Journal of Life Sciences
Volume 2, Issue 5, October 2014, Pages: 267-270
Received: Sep. 14, 2014; Accepted: Sep. 20, 2014; Published: Oct. 20, 2014
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Authors
Md. Reyad-Ul-Ferdous, Department of Pharmacy, Progati Medical Institute, Dhaka-1207, Bangladesh; Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
Sayma Akhter, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
Md. Zahirul Islam Khan, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
Md. Eshak Khan, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
Md. Atiqul Islam, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
Md. Sharif Ullah, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
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Abstract
In present study, the methanol extracts and all fractions of leaves of Bauhinia acuminata were subjected to various biological screening such as membrane stabilizing activity and antimicrobial screening. This investigation suggested that, leaves of Bauhinia acuminata were highly effective in the membrane stabilizing activity as the extractives prevented the lysis of erythrocyte by hypotonic solution and heat induced. In hypotonic solution induced condition the highest membrane stabilizing activity was exhibited by the Pet ether soluble fraction (PESF-418.26%) followed by carbon tetra chlororide soluble fraction (CTCSF-418.26%). Significant amount of membrane stabilizing activity were also present in methanol soluble fraction (MESF-13.46%) and aqueous soluble fraction (AQSF-167.30%). On the other hand, heat induced condition the maximum membrane stabilizing activity was exhibited by the carbon tetra chlororide soluble fraction (CTCSF-853.3%) followed by Methanol soluble fraction (MESF-423.88%). Significant amount of membrane stabilizing activity were also present in Pet ether soluble fraction (PESF-81.77%) and aqueous soluble fraction (AQSF-40.46%). In this study, the antimicrobial activity, among all extractives of leaves of Bauhinia acuminate was found to be negligible.
Keywords
Bauhinia Acuminate, Anti-Inflammatory, Antimicrobial Activity
To cite this article
Md. Reyad-Ul-Ferdous, Sayma Akhter, Md. Zahirul Islam Khan, Md. Eshak Khan, Md. Atiqul Islam, Md. Sharif Ullah, Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata, American Journal of Life Sciences. Vol. 2, No. 5, 2014, pp. 267-270. doi: 10.11648/j.ajls.20140205.13
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