Prevalence of Hepatitis B surface Antigen among the Newly Admitted Students of University of Jos, Nigeria
American Journal of Life Sciences
Volume 2, Issue 1, February 2014, Pages: 35-39
Received: Feb. 5, 2014;
Published: Feb. 28, 2014
Views 4143 Downloads 153
Odinachi Okoh Ekuma, Department of Science Laboratory Technology, Evangel University, Akaeze Abakaliki, Ebonyi State
John Danjuma Mawak, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Plateau State
Augustine Uwakwe, Department of Biochemistry, Evangel University, Akaeze Abakaliki, Ebonyi State
Ogbonnaya Ogbu, Department of Microbiology, Faculty of Biological Sciences, Ebonyi State University, Abakaliki Ebonyi State
Felicia Ngozi Okoh, Parasitology and Biomedical Diseases Research Unit, Department of Biological Sciences, Evangel University, Akaeze Abakaliki, Ebonyi
Maduka Victor Agah, Department of Microbiology, Faculty of Biological Sciences, Ebonyi State University, Abakaliki Ebonyi State
Agwu Ulu Nnachi, Department of Medical Microbiology and Parasitology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Anambra State
The study was conducted to assess the prevalence of Hepatitis B surface antigen (HBsAg) among the newly admitted students of University of Jos, Jos Nigeria. A total of 300 newly admitted students were screened using rapid test (Global Rapid Diagnostic Kits USA) for the detection of HBsAg in serum samples from July 2010 to October 2010. The results obtained showed that 50(16.7%) were seropositive to HBsAg. The prevalence of HBsAg was higher in males 34(11.33%) compared to 16(5.33%) in females. Age specific prevalence was significantly higher in the age bracket 25-29, with 16(28.57%) and the lowest was found in the age bracket 15 -19 years with 12(17.39%). The most important risk factors in the acquisition of HBsAg as revealed in this study appear to be: Family History of hepatitis, 11(36.6%), those with multiple sexual partners 4(13.79%), blood transfusion 3(13.64%), and tribal mark 3(13.04%). The prevalence of HBV recorded among newly admitted students in this study is probably a reflection of the situation in Nigerian Universities. Therefore, urgent preventive measures should be taken to set up campaign against transmission of HBV in University of Jos and the general population. To lower HBV prevalence, an adequate program of active screening and vaccination for students should be implemented, followed by a universal active immunization program.
Odinachi Okoh Ekuma,
John Danjuma Mawak,
Felicia Ngozi Okoh,
Maduka Victor Agah,
Agwu Ulu Nnachi,
Prevalence of Hepatitis B surface Antigen among the Newly Admitted Students of University of Jos, Nigeria, American Journal of Life Sciences.
Vol. 2, No. 1,
2014, pp. 35-39.
Ola, S.O., Odaibo, G.N. and Olaleye, O.D. HCV and HBV infections in Nigerian patients with liver cirrhosis and hepatocellular carcinoma. Nigerian Quarterly Journal of Hospital Medicine 2004, 14:3-4.
Barker, L.F., Shullam, R., Murray, R., Hirchman, R.J., Ratner, F., Diefenbach, W.C. and Geller, H.M. Transmission of serum hepatitis. Journal of the American Medical Association 1996, 276: 841-855.
Williams, R. Global challenges in liver disease. Hepatology 2006, 44(3): 521-526.
Maddrey, W.C. Hepatitis B an important public health issue. Journal of Medical Virology 2000, 61: 362-63.
Bojuwoye, B.J. The burden of viral hepatitis in Africa. West African Journal of Medicine 1997, 16 (4): 198-203.
Olumide, E.A. The distribution of HbsAg in Africa and the tropics. Report of population study in Nigeria. International Journal of Epidemiology 1996, 5(3): 279-289.
Nacos, B., Dao, B. and Dahourou, M. Hepatitis B surface antigen carriers state in pregnant women in Bobo Dioulasso (Burkinafaso) Dakar Med. 2000, 45(2) 188-190(8).
Agbede, O.O., Iseniyi, J.O., Kolawole M.O. and Ojuawo, A. Risk factors and seroprevalence of hepatitis B surface antigens in mothers and their pre-school age children in Ilorin, Nigeria. Therapy 2007, 4(1):67-72.
Otegbayo, J.A., Fasola, F.A. and Abja, A. Prevalence of hepatitis B surface antigens, risk factors for viral acquisition and serum transaminase among blood denors in Ibadan, Nigeria. Tropical Gastroenterology 2007, 24(4) 196-7.
Pyrsopoulos, N.T. and Jeffers, L. Hepatitis C in African Americans. Journal of Clinical Gastroenterology 2007, 41 (2):185-193
Butler, T.G., Dolan, K.A., Ferson, M.J., McGuinnes, L.M., Brown, P.R. and Robertson, P.W. Hepatitis B and C in New South Wales prisons: prevalence and risk factors. Medical Journal of Australia 1997, 166 (3): 127-130
Miranda, A.E., Vargus, P.M., St. Louis, M.E. and Vicina, M.C. Sexually Transmitted Diseases among female prisoners in Brazil: Prevalence and Risk factors. Sexually Transmitted Diseases 2000 27: 49-495
Mustapha, S.K., Bolori, M.T., Ajayi, N.A., Aggada, H.A., Pindiga, U.H., Gashau, W. and Khalil, M.I.A. Hepatocellular carcinoma in North-Eastern Nigeria. A prospective clinical study of 100 cases. The Internet Journal of Gastroenterology 2007, 6(1).
Federal Ministry of Health Nigeria. National HIV/AIDs and Reproductive Health Survey, Abuja 2003, 209pp.
UNSN. Nigeria Common Country Assessment World Health Organization, Geneva 2001, 563pp.
Hodges, M., Sanders, E. and Aitken, C. Seroprevalence of hepatitis markers: HAV, HBV, HCV and HEV among primary school children in Freetown Sierra Leon. West African Journal of Medicine 1998, 17(1):36-37.
Narcisse, P.K., Soulyman, B., Alexander, M., Josiane, L., Aubin, B. and Alain, L. F. The prevalence of hepatitis B virus markers in a cohort of students in Bangui, Central African Republic. BMC. Infectious Diseases 2010, 10:226.
Muhammad M.A., Sohail, Z.Z., Salman, A. M., Shahzad, S. Asif, N., Salmaan, S., Mehar, A. and Javed, A. B. Molecular Epidemiology of Hepatitis B Virus genotype in Pakistan. BMC Infectious Disease 2007, 7:115.
Olakayode, A., Lawal, A, S., Bakaney, L. N., Uche, A. O., Udeze, I., and Okonko, O. (2009). HBV infection among intending blood donors who incidentally tested positive of HIV Anti-body in two blood banks in Ibadan, Nigeria. World Applied Sciences Journal, 1(10) 12569-12754.
Alter, M. Epidemiology and prevention of hepatitis B. Seminars in Liver Disease 2003, 23(1): 39-46.
Yang, H.I., Lu, S.N., Liaw, Y.F., Yocu, S.L., Sun, C.A., Wang, L.Y., Hsiao, C.K., Chen, P.J., Chen, D.S. and Chen, C.J. Hepatitis B antigen and the risk of hepatocellular carcinoma. New England Journal of Medicine 2002, 347:168-174.