Personal Information
Ashok Kumar Pandurangan

Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Kuala Lumpur, Selangor, Malaysia

Ashok Kumar Pandurangan
Educations
From April 1999 to April 2002, B.Sc. , India
From April 2002 to April 2004, M.Sc. , India
From August 2005 to August 2006, M.Phil. , India
From August 2006 to August 2011, Ph.D , India
Work Experiences
From 05/2010 to 08/2012, Postdoctoral Fellow , Children's Hospital Oakland Research Institute, Oakland, CA, USA
From 04/2013 to 03/2015, Postdoctoral Fellow , Universiti Putra Malaysia, Serdang, Malaysia
From 04/15 to Till date, Visiting Research Fellow , University of Malaya, Kuala Lumpur, Malaysia
Speciality
Colon cancer
Inflammation associated cancer
Ulcerative colitis
Natural product Research
Acute pancreatitis
Journal Articles
Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: Involvement of caspase-3, NF-κB, and ERK. Molecular and Cellular Biochemistry, 311 (2008) 157-165, Sriram N, Kalayrasan S, Ashokkumar P, Sureshkumar A and Sudhandiran G.
Protective role of Luteolin on the status of lipid peroxidation and antioxidant defense against Azoxymethane-induced experimental colon carcinogenesis. Biomedicine & Pharmacotherapy, 62 (2008) 590-597, Ashokkumar P and Sudhandiran G.
Antioxidative and antiproliferative effects of astaxanthin during the initiation stages of 1,2-dimethyl hydrazine-induced experimental colon carcinogenesis. Fundamental and Clinical Pharmacology, 23 (2009) 225-234, Prabhu PN, Ashokkumar P and Sudhandiran G.
Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/β-catenin pathway. Investigational New Drugs, 29(2) (2011) 273-84, Ashokkumar P and Sudhandiran G.
Effect of Luteolin on the levels of Glycoproteins during Azoxymethane-induced colon carcinogenesis in mice. Asian Pacific Journal of Cancer Prevention, 13(4) (2012) 1569-73, Pandurangan AK, Dharmalingam P, Anandasadagopan SK, and Ganapasam S.
Chemopreventive sphingadienes downregulate wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. Carcinogenesis, 33(9) (2012) 1726-1735, Kumar A, Pandurangan AK, Lu F, Fyrst H, Zhang M, Byun HS, Bittman R and Saba JD.
Green tea polyphenol protection against 4-Nitroquinoline1-oxide-induced bone marrow lipid peroxidation and genotoxicity in wistar rats. Asian Pacific Journal of Cancer Prevention, 13(5) (2012) 4107-4112, Pandurangan AK, Periasamy S, Anandasadagopan SK, Ganapasam S and Chennam Srinivasalu S.
Luteolin induces apoptosis in azoxymethane-induced colon carcinogenesis through involvement of Bcl-2, Bax, and Caspase-3. Journal of Chemical and Pharmaceutical Research, 5(4) (2013) 143-148, Pandurangan AK and Ganapsam S.
Potential targets for the prevention of colorectal cancer: A focus on PI3K/Akt/mTOR and Wnt pathways. Asian Pacific Journal of Cancer Prevention, 14(4) (2013) 2201-2205. Pandurangan AK.
Inhibitory effect of Luteolin on the status of membrane bound ATPases against Azoxymethane-induced colorectal cancer. Journal of Chemical and Pharmaceutical Research, 5(6) (2013) 123-127, Pandurangan AK, Dharmalingam P, Anandasadagopan SK and Ganapasam S.
Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/β-catenin/GSK-3β signaling. Journal of Environmental Pathology, Toxicology, Oncology, 32(2) (2013) 131-139, Pandurangan AK, Dharmalingam P, Ananda Sadagopan SK, Ramar M, Munusamy A and Ganapasam S.
Dietary non-nutritive factors on regulatory molecules in colorectal cancer: An update. Asian Pacific Journal of Cancer Prevention, 14 (10) (2013) 5543-5552, Pandurangan AK and Esa NM.
Preventive Inositol Hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β-catenin and COX-2 pathways. BioMed Research International, 2013 (2013) 681027, Shafie NH, Mohd Esa NM, Ithnin H, Akim AM, Saad N, Pandurangan AK.
Cytotoxic effect of Luteolin on human colorectal cancer cell line (HCT-15): Crucial involvement of Reactive oxygen species. Middle East Journal of Cancer, 4(4) (2013) 177-182, Pandurangan AK* and Ganapasam S.
Pro-apoptotic effect of rice bran inositol hexaphosphate (IP6) on HT-29 colorectal cancer cells. International Journal of Molecular Sciences, 14 (2013) 23545-23558, Shafie NH, Esa NM, Ithnin H, Akim AM, Saad N, Pandurangan AK.
Luteolin, a bioflavonoid attenuates Azoxymethane-induced effects on mitochondrial enzymes in Balb/c mice. Asian Pacific Journal of Cancer Prevention, 14(11) (2013) 6669-6672, Pandurangan AK and Ganapasam S.
Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through Nrf2 signaling. Toxicology Mechanisms & Methods, 24(1) (2014) 13-20, Pandurangan AK, Ananda Sadagopan SK, Dharmalingam P and Ganapasam S.
Signal Transducer and Activator of Transcription 3: A Promising target in colitis associated cancer. Asian Pacific Journal of Cancer Prevention, 15(2) (2014) 551-560, Pandurangan AK and Norhaizan ME.
Luteolin inhibits Matrix metalloproteinase 9 and 2 in Azoxymethane-induced colon carcinogenesis. Human and Experimental Toxicology, (Equb Ahead of Print), DOI: 10.1177/0960327114522502, Pandurangan AK, Ananda Sadagopan SK, Dharmalingam P and Ganapasam S.
Inhibitory effect of Luteolin on Azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2. Pharmacognosy Magazine, 2014, 10(38) (2014) 306-310, Pandurangan AK, Ananda Sadagopan SK, Dharmalingam P and Ganapasam S.
Luteolin a bioflavonoid inhibits colorectal cancer through modulation of multiple signaling pathways: A review. Asian Pacific Journal of Cancer Prevention, 15(14) (2014) 5501-5508, Pandurangan AK and Esa NM.
S1P lyase (SPL) downregulation: a reversible step in colon carcinogenesis that promotes cell transformation through STAT3-activated miRNAs. Journal of Clinical Investigation, 124(12) (2014) 5368-84, Degagne E, Pandurangan A, Bandhuvula PV, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, Jong PD, Fong LG, Young SG, Ahmedi Y and Saba JD.
Dietary Cocoa protects against colitis-associated cancer by activating Nrf2/Keap1 pathway. BioFactors, 41(1) (2015) 1-14, Pandurangan AK#, Saadatdoust Z, Esa NM, Hamzah H, Ismail A.
Allicin alleviates Dextran sodium sulfate (DSS)-induced ulcerative colitis in BALB/c mice. Oxidative Medicine and Cellular Longevity, Article ID:605208 (2015) 15, Pandurangan AK, Ismail S, Saadatdoust Z and Esa NM.
Gallic acid attenuates dextran sodium sulfate (DSS)-induced experimental acute ulcerative colitis in BALB/c mice. Drug, Design, Development and Therapy, 9 (1) (2015) 3932-3934, Pandurangan AK, Mohebali N, Norhaizan ME, Looi CY.
Effect of Luteolin on carbohydrate-metabolizing enzymes in Azoxymethane-induced colon carcinogenesis. International Journal of Oncotherapy, 1(1) (2015) 6-10, Pandurangan AK and Ganapasam S.
Modifying effect of Luteolin on bacterial enzymes activity during Azoxymethane-induced colon cancer in mice. International Journal of Oncotherapy, 1(1) (2015) 15-18, Pandurangan AK and Ganapasam S.
Hydrogen peroxide impedes NK cell and T cell mediated cytotoxicity against colon cancer cells. International Journal of Oncotherapy, 1(1) (2015) 23-28, Subramani B, Pullai CR, Radzuan E, Pandurangan AK, Chinnasamy A, Sellamuthu Subbanna Gounder S.
Gallic acid suppresses inflammation of dextran sodium sulfate-induced colitis in mice: possible mechanisms. International Immunopharmacology, 28(2) (2015) 1034-43, Pandurangan AK, Mohebali N, Norhaizan ME, Looi CY, Salmiah I and Saadatdoust Z.
Targeting interleukin-17 a novel approach to treat colitis-associated cancer. International Journal of Oncotherapy, 1(2) (2015) 29-31, Pandurangan AK and Muthu R.
Honors and Awards
Prof. Radha Shanmugasundaram Award for best thesis in 2011 from University of Madras, Chennai
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186