Personal Information
Chenjuan Gu

Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA

Chenjuan Gu
Educations
From 09/2015 to 06/2018, PHD , China and USA
From 07/2018 to present, Postdoctoral Research Fellowship , USA
From 08/2013 to 08/2016, Fellowship , China
From 07/2011 to 07/2013, Residency , China
From 09/2004 to 06/2011, Bachelor & Master of Medicine , China
Work Experiences
From 08/2013 to 03/2018, Physician , Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Projects
From 01/2015 to 12/2017, Study on roles of c-Jun NH2-terminal kinase pathway in the development of insulin resistance induced by chronic intermittent hypoxia
Speciality
Sleep disordered breathing
Pulmonary and critical care
Metabolism
Book
Mechanisms and Manifestations of Obesity in Lung Disease, 2019 Elsevier Inc, Chapter 8: 169-200. ISBN: 978-0-12-813553-2
Journal Articles
 Gu CJ, Yi HH, Feng J, Zhang ZG, Zhou J, Zhou LN, Zhou JP, Li M, Li QY. Intermittent Hypoxia Disrupts Glucose Homeostasis in Liver Cells in an Insulin-Dependent and Independent Manner. Cell Physiol Biochem,2018;47(3):1042-1050.
 Gu C, Jun JC. Does Hypoxia Decrease the Metabolic Rate? Front Endocrinol (Lausanne),2018; 9:668.
 Gu C, Jun JC. Continuous Positive Airway Pressure Titration: A Minor Change Can Make a Major Difference. Ann Am Thorac Soc, 2018;15(9):1105-1107.
 Gu C, Younas H, Jun JC. Sleep apnea: An overlooked cause of lipotoxicity? Med Hypotheses, 2017;108:161-165.
 Yi H, Gu C, Li M, Zhang Z, Li Q, Feng J, Zhou J, Du J. PERK/eIF2α contributes to changes of insulin signaling in HepG2 cell induced by intermittent hypoxia. Life Sci, 2017;181:17-22.
 Younas H, Vieira M, Gu C, Lee R, Shin MK, Berger S, Loube J, Nelson A, Bevans-Fonti S, Zhong Q, D'Alessio FR, McCormack MC, Hansel NN, Mitzner W, Polotsky VY. Caloric restriction prevents the development of airway hyperresponsiveness in mice on a high fat diet. Sci Rep, 2019;9(1):279.
 Chopra S, Rathore A, Younas H, Pham LV, Gu C, Beselman A, Kim IY, Wolfe RR, Perin J, Polotsky VY, Jun JC. Obstructive Sleep Apnea Dynamically Increases Nocturnal Plasma Free Fatty Acids, Glucose, and Cortisol During Sleep. J Clin Endocrinol Metab, 2017;102(9):3172-3181.
 Caballero-Eraso C, Shin MK, Pho H, Kim LJ, Pichard LE, Wu ZJ, Gu C, Berger S, Pham L, Yeung HB, Shirahata M, Schwartz AR, Tang WW, Sham JSK, Polotsky VY. Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response. J Physiol, 2019;597(1):151-172.
 Gu CJ, Li M, Li QY, Li N, Shi GC, Wan HY. Obstructive sleep apnea is associated with impaired glucose metabolism in Han Chinese subjects. Chin Med J (Engl),2013;126(1):5-10.
 Gu CJ, Li M, Li QY, Li N. Chronic intermittent hypoxia increases β cell mass and activates the mammalian target of rapamycin/hypoxia inducible factor 1/vascular endothelial growth factor A pathway in mice pancreatic islet. Chin Med J (Engl), 2013;126(12):2368-73.
Conference Papers
 Gu, C; Yi, H; Feng, J; Zhang, Z; Zhou, J; Li, M; Li, Q. Intermittent Hypoxia Disrupted Insulin Signaling and Glucose Homeostasis in Liver Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE,2018; Volume:197. Meeting Abstract: A6406.
 Gu, C; Li, M; Li, Q; Zhou, J; Du, J; Yi, H; Feng, J. Serum Gamma-Glutamyltransferase In Obstructive Sleep Apnea And Its Role In Predicting Concomitant Diabetes Mellitus. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016; Volume: 193. Meeting Abstract: A7440.
 Gu, CJ; Chen, H; Ding, YJ; Shi, GC. Cytomegalovirus Infection After Severe Pneumonia in Immunocompetent Subjects: A Two-Case Report. CHEST, 2016; 149(4): 121A-121A.
 Gu, CJ; Li, QY; Li, M; Zhou, J; Du, J; Yi, HH. Liver Enzymes and Lipid Profile in Han Chinese Subjects With Obstructive Sleep Apnea. CHEST, 2016; 149(4): 574A-574A.
 C. Gu, M. Li, Q. Li, N. Li. Changes Of Islet Beta Cell Mass And MTOR/HIF1/VEGF-A Pathway In Mice Exposed To Intermittent Hypoxia. (2012 ATS, oral presentation)
 C. Gu, M. Li, Q. Li. Impaired Glucose Tolerance And Pancreatic Beta Cell Function in Patients with Obstructive Sleep Apnea. (2012 ATS, poster presentation)
Honors and Awards
 The best oral research presentation at the 3RD ANNUAL JOHNS HOPKINS UNIVERSITY SLEEP AND CIRCADIAN RESEARCH DAY. Johns Hopkins University, 2017
 American Thoracic Society International Trainee Travel Award. ATS, 2012, San Francisco, California, USA.
 Excellent Paper Award for National Sleep-Disordered Breathing Conference. Chinese Sleep Research Society, 2016
 Excellent English Paper Award for Young and Middle Aged Respiratory Academic Forum. Chinese Thoracic Society, 2012
 Excellent Paper Award for Chinese Sleep Medicine Congress. Chinese Medical Doctor Association, 2012
 Excellent Paper Award for National Sleep-Disordered Breathing Conference. Chinese Sleep Research Society, 2012
 Excellent Paper Award for National Respiratory Conference. Chinese Thoracic Society, 2011
ADDRESS
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Tel: (001)347-983-5186