Personal Information
Ayantika Sen

Department of Biochemistry and Microbiology, Oklahoma State University, Tulsa, Oklahoma, USA

Ayantika Sen
Educations
From August 2014 to August 2019, Doctorate , USA
Work Experiences
From August 2019 to Present, Postdoctoral Research Associate , Oklahoma State University Center for Health Sciences
Projects
From August 2014 to August 2019, Estrogen receptors differentially modulate innate immunity in the urinary tract in response to urinary tract infection , • Identified the role of estrogen receptors in regulating immune responses against Dr E. coli infection in human bladder cells • Identified the role of estrogen receptor alpha in regulating immune responses in the murine urinary tract • Developed and standardized protocols for studying pre- and post-infection cytokine responses in human bladder cells pre-treated with hormonal drugs
From August 2014 to August 2019, Immunomodulatory effects of Diamond Nanoparticles in response to urinary tract infection , • Identified the effects of diamond nanoparticles on cytokine secretion in the murine urinary tract in response to urinary tract infections
From January 2014 to May 2014, In-silico identification and analysis of deleterious missense mutations in WAS gene causing Wiskott-Aldrich syndrome: a computational and molecular dynamics (MD) approach” , • Identified deleterious missense mutations in WAS gene, and predicted the type of functional abnormalities that these mutations may render in the WAS protein, using a molecular dynamics approach
From January 2013 to December 2013, Computational prediction and mutation analysis of SNP bearing region of Exon-13 of USP9Y gene in azoospermic patients , • Using computational prediction methods, identified probable deleterious single nucleotide polymorphisms in exon-13 of USP9Y gene in blood samples of azoospermic patients of Indian origin
Speciality
Immunology, Infectious diseases, Estrogen Biology
Journal Articles
Estrogen Receptor Alpha Differentially Modulates Host Immunity in the Bladder and Kidney in Response to Urinary Tract Infection. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627544/
Clinical, Cytogenetic and CYP1A1 exon-1 Gene Mutation Analysis of Beedi Workers in Vellore Region, Tamil Nadu. https://pubmed.ncbi.nlm.nih.gov/24460333/
Estrogen receptors in human bladder cells regulate innate cytokine responses to differentially modulate uropathogenic E. coli colonization. (pre-print) bioRxiv 2020.05.27.120089; doi: https://doi.org/10.1101/2020.05.27.120089
Conference Papers
A Sen, J K Iyer, A Dickey, A Kaul, C McDonald, R Kaul. Distinct role of Estrogen Receptor α agonist and antagonist on urinary tract infection outcome in bladder versus kidney. Federation Of Clinical Immunology Society conference, Chicago, 2017
A Sen, S Boddu, J K Iyer, A Kaul, R Kaul. Estrogen Receptor Alpha agonist and antagonist differentially modulate host immunity during Urinary Tract Infection. 5th European Congress of Immunology, Amsterdam, 2018
A Sen, S Boddu, S Raj, R Synar, J K Iyer, A Kaul, R Kaul. Estrogen Receptor Alpha Antagonist Mediates Therapeutic Benefit against Urinary Tract Infection by Boosting TNFα Production in Bladder. Presented at the Federation of Clinical Immunology Society conference, San Francisco, 2018
A Sen, J K Iyer, A Dickey, A Kaul, R Kaul. Selective Estrogen Receptor Modulators differentially regulate Urinary Tract Infection outcome in the bladder and kidney. Cells vs. Pathogens Intrinsic Defenses and counter-defenses Keystone conference, Monterey, 2018
A Sen, S Rajiv, N Sekar, VG Abilash. Computational Prediction and Mutation Analysis of SNP Bearing Region of Exon-13 of USP9Y gene in Azoospermic Patients. National University of Singapore – Vellore Institute of Technology (NUS-VIT) International Symposium, Vellore, December 2013
Invited Talks
“How does estrogen modulate our immune systems to protect us from Urinary Tract Infections?” presented at OSU Women’s Faculty Council Award Ceremony, Stillwater, April 17, 2018
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186